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Radiology. 1994 Nov;193(2):341-4.

Percutaneous adrenal biopsy: review of a 10-year experience.

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  • 1Department of Radiology, Mayo Clinic, Rochester, MN 55905.



To evaluate the indications for and complications, accuracy, and techniques of percutaneous adrenal biopsy performed from 1982 through 1991 at the authors' institution.


Two hundred seventy-seven percutaneous adrenal biopsies were performed in 270 patients (175 male and 102 female patients, aged 31-84 years). Imaging studies and histories were reviewed, and each patient's case was followed up for at least 1 year after the biopsy. A patient was excluded from the study only if follow-up data could not be obtained.


The accuracy of percutaneous adrenal biopsy was 90% (249 of 277 biopsies). In the first 5 years of the study, the accuracy was 85% (87 of 102 biopsies); in the latter 5 years it was 93% (163 of 175 biopsies). The sensitivity was 81%, and the specificity was 99%. The positive predictive value was 99%, and the negative predictive value was 80%. The complication rate was 2.8%.


Percutaneous biopsy is a safe, accurate procedure for the diagnosis of pathologic conditions of the adrenal glands. The most common indication for a biopsy is the presence of an adrenal mass in a patient with lung cancer.

[PubMed - indexed for MEDLINE]
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