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Semin Immunol. 1994 Jun;6(3):143-53.

The mechanism of V(D)J recombination: site-specificity, reaction fidelity and immunologic diversity.

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  • 1Department of Pathology, Stanford University School of Medicine, CA 94305-5324.

Abstract

Site-specific recombination reactions in higher eukaryotes are uncommon, perhaps because of the potential genomic instability that they may create. We focus this review on the issues of site-specificity, reaction fidelity and immunologic diversity in the V(D)J recombination reaction.

PMID:
7948954
[PubMed - indexed for MEDLINE]

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