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    Nucleic Acids Res. 1994 Sep;22(17):3640-59.

    Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases.

    McClelland M, Nelson M, Raschke E.

    Source

    California Institute of Biological Research, La Jolla 92037.

    Abstract

    Restriction endonucleases have site-specific interactions with DNA that can often be inhibited by site-specific DNA methylation and other site-specific DNA modifications. However, such inhibition cannot generally be predicted. The empirically acquired data on these effects are tabulated for over 320 restriction endonucleases. In addition, a table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned genes.

    PMID:
    7937074
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC308336
    Free PMC Article

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