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Fertil Steril. 1994 Nov;62(5):921-5.

A prospective study comparing unilateral and bilateral laparoscopic ovarian diathermy in women with the polycystic ovary syndrome.

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  • 1Department of Reproductive Endocrinology, University College London, United Kingdom.

Abstract

OBJECT:

To assess the efficacy of unilateral laparoscopic ovarian diathermy in the induction of ovulation in anti-estrogen-resistant polycystic ovary syndrome (PCOS).

DESIGN:

A prospective randomized study was performed to compare unilateral with bilateral ovarian diathermy.

SETTING:

Specialist Reproductive Endocrine Unit.

PATIENTS:

Ten patients with anti-estrogen-resistant PCOS.

INTERVENTIONS:

Randomization to unilateral (4 patients) or bilateral laparoscopic ovarian diathermy (6 patients).

MAIN OUTCOME MEASURES:

Rate and side of ovulation and change in endocrine profiles after ovarian diathermy.

RESULTS:

Unilateral ovarian diathermy resulted in ovulation from both ovaries. Fifty percent of the patients responded to diathermy and those who responded had a significantly greater fall in serum LH concentrations than those who failed to respond.

CONCLUSIONS:

The mechanism of action of laparoscopic ovarian diathermy is via a correction of disturbed ovarian-pituitary feedback. Hypersecretion of LH appears to be the most significant endocrine disturbance in these patients.

PMID:
7926135
[PubMed - indexed for MEDLINE]
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