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Curr Opin Nephrol Hypertens. 1993 Jan;2(1):96-105.

Sympathetic neural mechanisms in human hypertension.

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  • 1University of Iowa College of Medicine, Iowa City.

Abstract

This review discusses the role of the sympathetic nervous system in the pathogenesis and maintenance of human hypertension. Three points are emphasized: first, there are mechanisms by which the sympathetic nervous system can contribute to the long-term regulation of vascular resistance and arterial pressure in addition to the moment-to-moment regulation of arterial pressure; second, the microneurographic method for direct intraneural recording of sympathetic nerve activity in humans has provided mounting evidence for increased sympathetic neural activity in human essential and renovascular hypertension; and third, there are both peripheral reflex and humoral mechanisms that may contribute to sympathetic overactivity in human hypertension.

PMID:
7922174
[PubMed - indexed for MEDLINE]
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