Identification of the 5' end of the gene encoding a human insulin-responsive glucose transporter.
Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi di Milano, Italy.
The 5' end of a gene (GLT4) encoding a human insulin-responsive glucose transporter was isolated from a human lambda Fix genomic library and sequenced. The human sequence, as compared to the mouse GLT4 promoter [Kaestner et al., Proc. Natl. Acad. Sci. USA 87 (1990) 251-255], revealed an overall homology of 81%. Putative transcription controlling sequences were identified.
PMID: 7916714 [PubMed - indexed for MEDLINE]