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Gene. 1993 Aug 25;130(2):307-8.

Identification of the 5' end of the gene encoding a human insulin-responsive glucose transporter.

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  • 1Dipartimento di Scienze e Tecnologie Biomediche, Universit√† degli Studi di Milano, Italy.


The 5' end of a gene (GLT4) encoding a human insulin-responsive glucose transporter was isolated from a human lambda Fix genomic library and sequenced. The human sequence, as compared to the mouse GLT4 promoter [Kaestner et al., Proc. Natl. Acad. Sci. USA 87 (1990) 251-255], revealed an overall homology of 81%. Putative transcription controlling sequences were identified.

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