Arch Intern Med. 1976 Nov;136(11):1290-3.

Kearns-Sayre syndrome. A review of a multisystem disorder of children and young adults.

Abstract

The syndrome of a slowly progressive external ophthalmoplegia, pigment retinopathy, and disorder of cardiac conduction was described by Kearns and Sayre in 1958. In patients with this triad, other neurological deficits may occur with associated abnormalities of the electrocardiogram, electroencephalogram, audiogram, and an elevation of protein in cerebrospinal fluid. The onset of a potentially lethal cardiac dysrhythmia in a patient with this slowly progressive degeneration of the nervous system can be anticipated and prevented by the use of an artivicial cardiac pacemaker.

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Chronic progressive external ophthalmoplegia, pigmentary retinopathy, and heart block (Kearns-Sayre syndrome). Report of a case. [Acta Ophthalmol (Copenh). 1975]
Chronic progressive external ophthalmoplegia, pigmentary retinopathy, and heart block (Kearns-Sayre syndrome). Report of a case.
Lowes M. Acta Ophthalmol (Copenh). 1975 Sep; 53(4):610-9.
[Conduction abnormalities in Kearns-Sayre syndrome. Observation of 2 clinical cases]. [Acta Cardiol. 1978]
[Conduction abnormalities in Kearns-Sayre syndrome. Observation of 2 clinical cases].
Gillet JM, Toppet M, Gallez A, Bernard R. Acta Cardiol. 1978; 33(5):323-9.
[Kearns syndrome. Progressive external ophthalmoplegia, retinal pigment degeneration and heart conduction disorders]. [Schweiz Med Wochenschr. 1977]
[Kearns syndrome. Progressive external ophthalmoplegia, retinal pigment degeneration and heart conduction disorders].
Boltshauser E, Jerusalem F, Niemeyer G, Huber C. Schweiz Med Wochenschr. 1977 Dec 17; 107(50):1880-8.
Review Kearns-Sayre syndrome: a case report and review. [Eur J Ophthalmol. 1992]
Review Kearns-Sayre syndrome: a case report and review.
Gross-Jendroska M, Schatz H, McDonald HR, Johnson RN. Eur J Ophthalmol. 1992 Jan-Mar; 2(1):15-20.
Review [Mitochondrial disease and complete heart block. Kearns-Sayre syndrome. Description of a case]. [Minerva Med. 1992]
Review [Mitochondrial disease and complete heart block. Kearns-Sayre syndrome. Description of a case].
Perocchio M, Tomassini B, Biasia R, Belli Valletta M, Cerutti A, Bobba F. Minerva Med. 1992 Dec; 83(12 Suppl 1):7-13.

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Cited by 3 PubMed Central articles

Mitochondrial cytopathy. A multisystem disorder with ragged red fibres on muscle biopsy. [Arch Dis Child. 1981]
Mitochondrial cytopathy. A multisystem disorder with ragged red fibres on muscle biopsy.
Egger J, Lake BD, Wilson J. Arch Dis Child. 1981 Oct; 56(10):741-52.
Hyperglycemic acidotic coma and death in Kearns-Sayre syndrome. [Trans Am Ophthalmol Soc. 1985]
Hyperglycemic acidotic coma and death in Kearns-Sayre syndrome.
Flynn JT, Bachynski BN, Rodrigues MM, Curless RG, Joshi B. Trans Am Ophthalmol Soc. 1985; 83:131-61.
Histopathology of mitochondrial cytopathy and the Laurence-Moon-Biedl syndrome. [Br J Ophthalmol. 1986]
Histopathology of mitochondrial cytopathy and the Laurence-Moon-Biedl syndrome.
Runge P, Calver D, Marshall J, Taylor D. Br J Ophthalmol. 1986 Oct; 70(10):782-96.

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