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Immunol Today. 1994 Apr;15(4):180-4.

CD26: a surface protease involved in T-cell activation.

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  • Dept of Medical Microbiology and Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.


CD26 is a proteolytic enzyme (dipeptidylpeptidase IV) with a wide tissue distribution and a unique specificity. Recent developments indicate that CD26 is a multifunctional molecule that may have important functions in the immune system. Here, Bernhard Fleischer reviews the current knowledge of CD26 and discusses the possible functions of this molecule in T lymphocytes.

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