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Biochim Biophys Acta. 1994 Jan 20;1210(3):369-72.

Acetyl-CoA carboxylase exerts strong flux control over lipid synthesis in plants.

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  • 1Department of Biochemistry, University of Wales College of Cardiff, UK.


The importance of acetyl-CoA carboxylase in regulation of lipid synthesis for barley and maize leaves has been quantitatively assessed using, as specific inhibitors, the herbicides fluazifop and sethoxydim. Apparent flux control coefficients of about 0.58 and 0.52 were determined for acetyl-CoA carboxylase in barley and maize leaves, respectively. These results show that acetyl-CoA carboxylase is the major flux controlling enzyme for light-stimulated lipid synthesis in these tissues.

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