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Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells.
Greenway AL, McPhee DA, Grgacic E, Hewish D, Lucantoni A, Macreadie I, Azad A.
Virology. 1994 Jan;198(1):245-56.
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