Trop Med Parasitol. 1994 Sep;45(3):219-22.

Plasmodium falciparum malaria: its effects on some haematological parameters in normal and sickle cell Nigerian children.

Source

Department of Biochemistry, College of Medical Sciences, University of Calabar, Nigeria.

Abstract

The effect of Plasmodium falciparum malaria on the iron status was determined in 80 children: normal children without malaria (20) and with malaria (20), and sickle cell anaemia without malaria (17) and with malaria (23). Iron status was assessed using serum transferrin, serum iron, transferrin saturation and haemoglobin. The non-malaria sickle cell anaemia (SCA) group had lower transferrin (234.0 +/- 21.0) and haemoglobin (8.1 +/- 0.4) than non-malaria normal group (260.6 +/- 17.1 mg/100 ml, and 12.5% respectively). Serum iron was higher in sickle cell anaemia (125.1 +/- 17.1) than non-malaria normals (119.2 +/- 1 microgram/100 ml). Malaria caused an increase in serum transferrin, TIBC and serum iron in both normal and SCA children; these changes were more dramatic in normal than in SCA children.

PMID:: 7899791; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Medical

Sickle Cell Anemia - MedlinePlus Health Information

Molecular Biology Databases

IRON - HSDB

Supplemental Content

Save items

Related citations in PubMed

Anaemia in acute, Plasmodium falciparum malaria in children from Orissa state, India. [Ann Trop Med Parasitol. 1999]
Anaemia in acute, Plasmodium falciparum malaria in children from Orissa state, India.
Das BS, Nanda NK, Rath PK, Satapathy RN, Das DB. Ann Trop Med Parasitol. 1999 Mar; 93(2):109-18.
Effect of Plasmodium falciparum parasitaemia on some haematological parameters in adolescent and adult Nigerian HbAA and HbAS blood genotypes. [Cent Afr J Med. 2002]
Effect of Plasmodium falciparum parasitaemia on some haematological parameters in adolescent and adult Nigerian HbAA and HbAS blood genotypes.
Eteng MU. Cent Afr J Med. 2002 Nov-Dec; 48(11-12):129-32.
Anaemia in young primigravidae in the guinea savanna of Nigeria: sickle-cell trait gives partial protection against malaria. [Ann Trop Med Parasitol. 1984]
Anaemia in young primigravidae in the guinea savanna of Nigeria: sickle-cell trait gives partial protection against malaria.
Fleming AF, Harrison KA, Briggs ND, Attai ED, Ghatoura GB, Akintunde EA, Shah N. Ann Trop Med Parasitol. 1984 Aug; 78(4):395-404.
Review Iron chelation therapy for malaria. [Adv Exp Med Biol. 1994]
Review Iron chelation therapy for malaria.
Gordeuk VR, Thuma PE, Brittenham GM. Adv Exp Med Biol. 1994; 356:371-83.
Review [Falciform anemia and Plasmodium falciparum malaria: a threat to flap survival?]. [Ann Chir Plast Esthet. 1999]
Review [Falciform anemia and Plasmodium falciparum malaria: a threat to flap survival?].
Mariéthoz S, Pittet B, Loutan L, Humbert J, Montandon D. Ann Chir Plast Esthet. 1999 Feb; 44(1):81-8.

See reviews... See all...

Cited by 1 PubMed Central article

An observational study of children with sickle cell disease in Kilifi, Kenya. [Br J Haematol. 2009]
An observational study of children with sickle cell disease in Kilifi, Kenya.
Sadarangani M, Makani J, Komba AN, Ajala-Agbo T, Newton CR, Marsh K, Williams TN. Br J Haematol. 2009 Sep; 146(6):675-82. Epub 2009 Jul 23.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Plasmodium falciparum malaria: its effects on some haematological parameters in ...
Plasmodium falciparum malaria: its effects on some haematological parameters in normal and sickle cell Nigerian children.
Trop Med Parasitol. 1994 Sep ;45(3):219-22.

PubMed
US, CT, and MR imaging of neck lesions in children.
US, CT, and MR imaging of neck lesions in children.
Radiographics. 1995 Jan ;15(1):105-22.

PubMed
Visible burrow system as a model of chronic social stress: behavioral and neuroe...
Visible burrow system as a model of chronic social stress: behavioral and neuroendocrine correlates.
Psychoneuroendocrinology. 1995 ;20(2):117-34.

PubMed
Morris Fishbein, MD-1889-1976, editor of JAMA-1924-1950.
Morris Fishbein, MD-1889-1976, editor of JAMA-1924-1950.
JAMA. 1976 Nov 8 ;236(19):2212.

PubMed
Effect of oral glutathione monoethyl ester and glutathione on circulating and he...
Effect of oral glutathione monoethyl ester and glutathione on circulating and hepatic sulfhydrils in the rat.
Pharmacol Toxicol. 1994 Dec ;75(6):343-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: