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Neurologia. 1995 Jan;10(1):37-40.

[Difficulties in differential diagnosis of long-term Creutzfeldt- Jakob disease].

[Article in Spanish]

Author information

  • 1Departamento de Neurología, University of Pittsburgh Medical Center, Pennsylvania.

Erratum in

  • Neurologia 1995 Apr;10(4):177.


Creutzfeldt-Jakob disease (CJD) is characterized by a rapidly progressive dementia that often leads to death within a few months of onset. However, some cases evolve over a much longer period of time and have a clinical picture that is difficult to distinguish from other progressive dementias that occur in the adult, especially Alzheimer's disease (AD). We examine the clinical features of 3 patients with pathologically confirmed CJD whose course was slow (4-5 years) and who were initially diagnosed as having AD. Only two of them had shown signs of CJD in the terminal stages. In this study we examine the clinical characteristics of these patients, and discuss of differentiating CJD from other entities, especially from AD.

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