Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
BMJ. 1995 Mar 4;310(6979):555-9.

Prospective study of cigarette smoking, alcohol use, and the risk of diabetes in men.

Author information

  • 1Harvard School of Public Health, Boston, Massachusetts 02115.

Abstract

OBJECTIVE:

To examine the association between smoking, alcohol consumption, and the incidence of non-insulin dependent diabetes mellitus in men of middle years and older.

DESIGN:

Cohort questionnaire study of men followed up for six years from 1986.

SETTING:

The health professionals' follow up study being conducted across the United States.

SUBJECTS:

41,810 male health professionals aged 40-75 years and free of diabetes, cardiovascular disease, and cancer in 1986 and followed up for six years.

MAIN OUTCOME MEASURE:

Incidence of non-insulin dependent diabetes mellitus diagnosed in the six years.

RESULTS:

During 230,769 person years of follow up 509 men were newly diagnosed with diabetes. After controlling for known risk factors men who smoked 25 or more cigarettes daily had a relative risk of diabetes of 1.94 (95% confidence interval 1.25 to 3.03) compared with non-smokers. Men who consumed higher amounts of alcohol had a reduced risk of diabetes (P for trend < 0.001). Compared with abstainers men who drank 30.0-49.9 g of alcohol daily had a relative risk of diabetes of 0.61 (95% confidence interval 0.44 to 0.91).

CONCLUSIONS:

Cigarette smoking may be an independent, modifiable risk factor for non-insulin dependent diabetes mellitus. Moderate alcohol consumption among healthy people may be associated with increased insulin sensitivity and a reduced risk of diabetes.

Comment in

PMID:
7888928
[PubMed - indexed for MEDLINE]
PMCID:
PMC2548937
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk