J Infect Dis. 1995 Mar;171(3):686-9.

Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection.

Anzala OA, Nagelkerke NJ, Bwayo JJ, Holton D, Moses S, Ngugi EN, Ndinya-Achola JO, Plummer FA.

Source

Department of Medical Microbiology, University of Nairobi, Kenya.

Erratum in

J Infect Dis 1996 Jun;173(6):1529.

Abstract

From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-1-related disease. The effect of several covariables on disease progression was studied using a Weibull proportional hazards model. The Weibull survival model was fitted to the observed incubation times. Estimates of the median duration to CDC stage IV-A and IV-C disease were 3.5 and 4.4 years, respectively. Condom use before seroconversion was associated with a reduced risk of CDC stage IV-A disease (relative risk = .64, P < .05). The incubation time of HIV-1-related disease is extremely short in this population.

Comment in

J Infect Dis. 1996 Jun;173(6):1526.

PMID:: 7876618; [PubMed - indexed for MEDLINE]

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Women and HIV - HIV InSite

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