Yeast. 1994 Nov;10(11):1497-502.

UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product.

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Department of Microbiology, University of Saskatchewan, Saskatoon, Canada.

Abstract

A gene from chromosome V of the yeast Saccharomyces cerevisiae has been cloned and sequenced. The deduced amino acid sequence encoded by this gene is similar to several ubiquitin-specific proteases from yeast, especially at the highly conserved domain. It is thus named UBP5. UBP5 is also closely related to the human Tre-2 and the mouse Unp oncogene products. This study adds a new member to the ubiquitin protease family and suggests that alteration of ubiquitin protease activity may result in cancer in mammals. However, disruption of the UBP5 gene in a haploid strain did not result in a noticeable phenotypic alteration.

PMID:: 7871889; [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

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UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the...
UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product.
Yeast. 1994 Nov ;10(11):1497-502.

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UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product.

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