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Insulin receptor disorders in Japan.
Second Department of Internal Medicine, Kobe University School of Medicine, Japan.
The clinical features of insulin receptor disorders found in Japan are summarized. About 20 cases of primary receptor mutations (type A syndrome of insulin resistance, leprechaunism and Rabson-Mendenhall syndrome) and 16 cases of autoantibodies against insulin receptor (type B syndrome of insulin resistance) are described in Japan. There was a trial of IGF-1 for some of the patients, revealing its usefulness.
PMID: 7859597 [PubMed - indexed for MEDLINE]
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