Department of Psychiatry, University of California, San Francisco 94143.
We describe eight patients with reversible MRI changes following seizures. The patients were mostly young with a serious underlying medical problem; MRI abnormalities were localized primarily in the posterior vascular boundary zones. A likely mechanism for these lesions is edema secondary to disruption in the blood-brain barrier. Recognition of the transient radiologic changes may aid in the diagnostic and therapeutic management of seizures.