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Fetal Diagn Ther. 1994 Sep-Oct;9(5):296-9.

Poor pregnancy outcome and anticardiolipin antibodies.

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  • 1Department of Obstetrics and Gynecology, Catholic University, Rome, Italy.

Abstract

The present study reports for the first time on the presence of anticardiolipin antibodies (aCL) in a population of 259 women with a history of recurrent abortion, intrauterine death, and/or neonatal death associated with fetal growth restriction, preeclampsia and abruptio placentae. The overall incidence of aCL in this study group was 20.5%, a statistically significant increase in comparison with a control group. The highest positive rate was observed among women who presented both recurrent abortion and intrauterine death (33.3%), the lowest was observed among women with a history of neonatal death. Our findings confirm that aCL are strongly linked with fetal loss. Thus, before planning a subsequent pregnancy, the presence of aCL should be tested in all women with poor pregnancy outcome.

PMID:
7818777
[PubMed - indexed for MEDLINE]
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