Cerebral artery stenoses in Williams syndrome cause strokes in childhood

P Kaplan; M Levinson; B S Kaplan

doi:10.1016/s0022-3476(95)70216-4

Cerebral artery stenoses in Williams syndrome cause strokes in childhood

J Pediatr. 1995 Jun;126(6):943-5. doi: 10.1016/s0022-3476(95)70216-4.

Authors

P Kaplan¹, M Levinson, B S Kaplan

Affiliation

¹ Children's Hospital of Philadelphia, PA 19104-4399, USA.

PMID: 7776101
DOI: 10.1016/s0022-3476(95)70216-4

Abstract

Extensive narrowing of lumens of many cerebral arteries caused strokes with brain damage and chronic hemipareses in two children with Williams syndrome. Increased irritability, loss of consciousness, and seizures were initial signs. Arterial stenoses are not limited to the supravalvular aorta and pulmonary arteries in patients with Williams syndrome.

Publication types

Case Reports

MeSH terms

Adult
Aortic Valve Stenosis / complications
Aortic Valve Stenosis / congenital
Cerebral Arterial Diseases / complications*
Cerebral Arterial Diseases / congenital*
Cerebrovascular Disorders / etiology*
Child, Preschool
Constriction, Pathologic
Female
Humans
Male
Vascular Diseases / complications
Vascular Diseases / congenital*