J Biotechnol. 1993 Jul;30(1):79-90.

Lignin-degrading peroxidases of Phanerochaete chrysosporium.

Source

Department of Molecular and Cell Biology, Pennsylvania State University, University Park 16802.

Abstract

Lignin and manganese peroxidases are secreted by the basidiomycete Phanerochaete chrysosporium during secondary metabolism. These enzymes play major roles in lignin degradation. The active site amino acid sequence of these lignin-degrading peroxidases is similar to that of horseradish peroxidase (HRP) and cytochrome c peroxidase (CcP). The mechanism by which they oxidize substrates also appears to be the similar. pH has a similar effect on lignin peroxidase compound I formation as on HRP or CcP; however, the pKa controlling compound I formation for lignin peroxidase appears to be much lower. Lignin-degrading peroxidases are able to catalyze the oxidation of substrates with high redox potential. This unique ability is consistent with a heme active site of low electron density, which is indicated by high redox potential.

PMID:: 7763834; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Spectral characterization of manganese peroxidase, an extracellular heme enzyme from the lignin-degrading basidiomycete, Phanerochaete chrysosporium. [J Biol Chem. 1988]
Spectral characterization of manganese peroxidase, an extracellular heme enzyme from the lignin-degrading basidiomycete, Phanerochaete chrysosporium.
Mino Y, Wariishi H, Blackburn NJ, Loehr TM, Gold MH. J Biol Chem. 1988 May 25; 263(15):7029-36.
Characterization of extracellular peroxidases produced by acetate-buffered cultures of the lignin-degrading basidiomycete Phanerochaete chrysosporium. [FEMS Microbiol Lett. 1990]
Characterization of extracellular peroxidases produced by acetate-buffered cultures of the lignin-degrading basidiomycete Phanerochaete chrysosporium.
Dass SB, Reddy CA. FEMS Microbiol Lett. 1990 Jun 1; 57(3):221-4.
Description of a versatile peroxidase involved in the natural degradation of lignin that has both manganese peroxidase and lignin peroxidase substrate interaction sites. [J Biol Chem. 1999]
Description of a versatile peroxidase involved in the natural degradation of lignin that has both manganese peroxidase and lignin peroxidase substrate interaction sites.
Camarero S, Sarkar S, Ruiz-Dueñas FJ, Martínez MJ, Martínez AT. J Biol Chem. 1999 Apr 9; 274(15):10324-30.
Review Physiology and molecular biology of the lignin peroxidases of Phanerochaete chrysosporium. [FEMS Microbiol Rev. 1994]
Review Physiology and molecular biology of the lignin peroxidases of Phanerochaete chrysosporium.
Reddy CA, D'Souza TM. FEMS Microbiol Rev. 1994 Mar; 13(2-3):137-52.
Review Molecular biology of the lignin-degrading basidiomycete Phanerochaete chrysosporium. [Microbiol Rev. 1993]
Review Molecular biology of the lignin-degrading basidiomycete Phanerochaete chrysosporium.
Gold MH, Alic M. Microbiol Rev. 1993 Sep; 57(3):605-22.

See reviews... See all...

Cited by 2 PubMed Central articles

Mechanism for oxidation of high-molecular-weight substrates by a fungal versatile peroxidase, MnP2. [Appl Environ Microbiol. 2008]
Mechanism for oxidation of high-molecular-weight substrates by a fungal versatile peroxidase, MnP2.
Tsukihara T, Honda Y, Sakai R, Watanabe T, Watanabe T. Appl Environ Microbiol. 2008 May; 74(9):2873-81. Epub 2008 Mar 7.
Expression of lignin peroxidase H8 in Escherichia coli: folding and activation of the recombinant enzyme with Ca2+ and haem. [Biochem J. 1996]
Expression of lignin peroxidase H8 in Escherichia coli: folding and activation of the recombinant enzyme with Ca2+ and haem.
Doyle WA, Smith AT. Biochem J. 1996 Apr 1; 315 ( Pt 1):15-9.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Lignin-degrading peroxidases of Phanerochaete chrysosporium.
Lignin-degrading peroxidases of Phanerochaete chrysosporium.
J Biotechnol. 1993 Jul ;30(1):79-90.

PubMed
The Trichoderma cellulase regulatory puzzle: from the interior life of a secreto...
The Trichoderma cellulase regulatory puzzle: from the interior life of a secretory fungus.
Enzyme Microb Technol. 1993 Feb ;15(2):90-99.

PubMed
Transcription factor based therapeutics: drugs of the future?
Transcription factor based therapeutics: drugs of the future?
Trends Biotechnol. 1993 Jan ;11(1):11-8.

PubMed
Identification of a genetic mutation in a family with fructose-1,6- bisphosphata...
Identification of a genetic mutation in a family with fructose-1,6- bisphosphatase deficiency.
Biochem Biophys Res Commun. 1995 May 25 ;210(3):797-804.

PubMed
A double-blind comparison of lithium carbonate and maprotiline in the prophylaxi...
A double-blind comparison of lithium carbonate and maprotiline in the prophylaxis of the affective disorders.
Br J Psychiatry. 1976 May ;128:479-85.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: