Send to:

Choose Destination
See comment in PubMed Commons below
Virus Res. 1995 Feb;35(2):113-21.

Viral oncoprotein binding to pRB, p107, p130, and p300.

Author information

  • 1Department of Biochemistry, School of Medicine and Dentistry, Rochester, NY 14642, USA.


The purpose of this review is to bring attention to some additional work in the tumor virus/tumor suppressor field which may have been overshadowed by reports describing adenovirus, SV40, and HPV oncoprotein binding to pRB and p53. The data reviewed herein provide further support for the model that a common mechanism by which DNA tumor viruses transform cells involves inactivation of cellular proteins which function as negative regulators of cell growth.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk