Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Chromatogr B Biomed Appl. 1995 Feb 3;664(1):225-31.

Preparative high-performance liquid chromatographic separation of proteins with HyperD ion-exchange supports.

Author information

  • 1BioSepra SA, Villeneuve la Garenne, France.

Abstract

HyperD ion-exchange media combine the mechanical strength of a rigid polystyrene-mineral composite skeleton with the high protein-binding capacity of a three-dimensional soft gel located inside the skeleton. The skeleton solid matrix is completely filled with functionalized, highly hydrophilic, chemically stable ion-exchange hydrogels. These materials gave very efficient columns for protein separation with superior dynamic capacity, high resolving power and excellent protein recovery. Various protein mixtures were used to study the chromatographic performance of these new stationary phases. Comparisons between different particle size packing materials demonstrated the potential of this ion-exchange material for use on a large scale.

PMID:
7757229
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk