Refined localization of human peroxisomal 3-oxoacyl-CoA thiolase (ACAA) to 3p22

Hum Hered. 1995 Mar-Apr;45(2):75-9. doi: 10.1159/000154263.

Abstract

The chromosomal localisation of the human gene coding for peroxisomal 3-oxoacyl-CoA thiolase (ACAA) was determined by human-hamster somatic cell hybrids and fluorescence in situ hybridisation, using cDNA and genomic probes, respectively. The results allowed an exclusion of the previously suggested presence of a second site for ACAA on chromosome 11 and an assignment of the gene to a single chromosome band (3p22).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetyl-CoA C-Acyltransferase / genetics*
  • Animals
  • Chromosome Mapping / methods*
  • Chromosomes, Human, Pair 3*
  • Cricetinae
  • DNA Probes
  • Humans
  • Hybrid Cells
  • In Situ Hybridization, Fluorescence
  • Microbodies / enzymology*

Substances

  • DNA Probes
  • Acetyl-CoA C-Acyltransferase