Curr Opin Genet Dev. 1995 Feb;5(1):44-50.

The Ras signaling pathway in Drosophila.

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Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California at Berkeley 94720-3200, USA.

Abstract

During Drosophila eye development, a Ras cascade mediates the decision between neuronal and non-neuronal differentiation of the R7 photoreceptor precursor. Recent genetic and molecular studies have identified a set of protein kinases as components of the Ras cascade and nuclear targets of the cascade, including Yan, Pointed, Jun, and Phyllopod. The Ras cascade functions in other Drosophila signal transduction pathways, eliciting a distinct response in each case, presumably through phosphorylation of specific transcription factors.

PMID:: 7749324; [PubMed - indexed for MEDLINE]

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The Ras signaling pathway in Drosophila.

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