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    Virology. 1995 May 10;209(1):230-5.

    Glycoprotein B of bovine herpesvirus-1 binds heparin.

    Source

    Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.

    Abstract

    Many members of the herpesvirus family have been shown to bind heparan sulfate on the surface of target cells. A previous report on bovine herpesvirus-1 (BHV-1) glycoprotein interactions indicated that only gC bound to heparin-agarose columns. In this report, we demonstrated that both gC and gB of wild-type BHV-1 bound to heparin-agarose columns and that gC-minus virus infectivity was inhibited by heparin.

    PMID:
    7747474
    [PubMed - indexed for MEDLINE]

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