Total support of the circulation of a patient with post-cardiotomy stone-heart syndrome by a partial artificial heart (ALVAD) for 5 days followed by heart and kidney transplantation

Lancet. 1978 May 27;1(8074):1125-7. doi: 10.1016/s0140-6736(78)90301-x.

Abstract

A patient with acute bacterial endocarditis in whom ischaemic contracture of the left ventricle (stone-heart syndrome) developed during aortic and mitral valve replacement had an emergency implantation of an intracorporeal partial artificial heart (an abdominal left-ventricular assist device of ALVAD). This device functioned as a total artificial heart for nearly 6 days, while a donor heart for transplantation was sought. The ALVAD was then removed, and the patient received allografts of a heart and a kidney. The transplanted heart functioned well, but the patient died 15 days later from gram-negative sepsis. There was no evidence of cardiac or renal allograft rejection.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Aortic Valve / surgery
  • Assisted Circulation / instrumentation*
  • Contracture / etiology
  • Coronary Disease / etiology
  • Coronary Disease / therapy*
  • Endocarditis, Bacterial / surgery
  • Heart Transplantation*
  • Heart Valve Prosthesis / adverse effects
  • Heart, Artificial*
  • Humans
  • Intra-Aortic Balloon Pumping / instrumentation*
  • Kidney Transplantation*
  • Male
  • Mitral Valve / surgery
  • Muscle Contraction
  • Myocardium / pathology
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy*
  • Syndrome
  • Time Factors
  • Transplantation, Homologous