Abstract
The effects of essential oil of Croton zehntneri (Euphorbiaceae), orally administered were studied on behavioral parameters using rats and mice. The oil suspension did not modify pentobarbital induced-hypnosis, stereotypic behavior, catalepsy and amphetamine-induced hypermotility. The open-field behaviors were decreased and the minimal convulsant dose of pentylenetetrazole was increased.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amphetamine / pharmacology
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Animals
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Anticonvulsants / pharmacology
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Behavior, Animal / drug effects*
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Brazil
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Catalepsy / chemically induced
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Croton Oil / pharmacology*
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Male
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Mice
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Motor Activity / drug effects
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Pentobarbital / pharmacology
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Pentylenetetrazole / antagonists & inhibitors
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Plants, Medicinal / chemistry
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Rats
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Rats, Wistar
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Sleep / drug effects
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Stereotyped Behavior / drug effects
Substances
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Anticonvulsants
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Croton Oil
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Amphetamine
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Pentobarbital
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Pentylenetetrazole