J Intern Med. 1995 May;237(5):507-18.

Analysis of the MRFIT screenees: a methodological study.

Source

Swedish Council on Technology Assessment in Health Care, Stockholm.

Abstract

PURPOSE:

To review the methods used in the many publications on the MRFIT screenees.

METHOD:

Medline was searched for articles mentioning MRFIT screenees. The articles were collected, abstracted, and the method section and some of the result section were scrutinized in detail. The statements in different articles regarding methods used and the presentation of results were compared.

RESULT:

The analyses of the MRFIT screenees seem to be retrospective studies of mortality and risk factors, where the underlying data base has been far from complete. Similar data are presented in slightly different fashions in several papers published in different scientific journals at about the same time. The control of the quality of underlying data has been uneven and is not discussed at all in most of the papers published.

CONCLUSION:

The often-repeated statement that the MRFIT screenees constitute the largest and most exact data base regarding the relation of risk factors to mortality in the healthy male US population has no foundation.

PMID:: 7738492; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Meta-Analysis

MeSH Terms

Substances

Cholesterol

LinkOut - more resources

Medical

ClinicalTrials.gov

Molecular Biology Databases

CHOLESTEROL - HSDB

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