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Vopr Virusol. 1994 Sep-Oct;39(5):205-8.

[Biological properties and antigenic interconnection between Tiuleniy and Karshi flaviviruses].

[Article in Russian]


Biological properties of flaviviruses Tyuleny and Karshi, new for the science, were studied. The viruses are highly pathogenic for laboratory animals; they replicate fairly well in primary chick embryo cells and PS cells. BHK-21 cells were found susceptible to replication of Karshi virus. Tyuleny and Karshi viruses were found capable of initiating and maintaining a persistent infection in primary brain cell cultures from suckling Syrian hamsters for at least 3 months. Both the viruses showed cytoproliferative activity in respect of the above cells in tissue cultures. Our data indicate that Tyuleny virus, a member of a separate antigenic group, is more closely related to Japanese encephalitis virus (strain JaGar 01), and Karshi virus to Powassan virus.

[PubMed - indexed for MEDLINE]
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