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Dermatol Clin. 1995 Jan;13(1):57-63.

HLA-linked hemochromatosis and other forms of iron overload.

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  • 1Department of Medicine, University of the Witwatersrand Medical School, Johannesburg, South Africa.


Inherited forms of iron overload are common. HLA-linked hemochromatosis and possibly African iron overload are associated with a significant risk of developing hepatocellular carcinoma. Early diagnosis and treatment, before substantial iron overloading occurs, reduces morbidity and mortality. HLA-linked hemochromatosis is easily diagnosed, and routine screening in European-derived populations may be appropriate.

[PubMed - indexed for MEDLINE]
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