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    Brain Res Mol Brain Res. 1995 Jan;28(1):175-9.

    Cloning, sequence analysis and expression of two forms of mRNA coding for the human beta 2 subunit of the GABAA receptor.

    McKinley DD, Lennon DJ, Carter DB.

    Upjohn Company, Kalamazoo, MI 49001.

    Two forms of cDNA coding for the human GABAA beta 2 subunit have been cloned and sequenced. The two sequences differ by a 114 base pair insertion. The insert contains a phosphorylation consensus sequence for calmodulin-dependent protein kinase II. Quantitative PCR studies show that h beta 2L cDNA represents 10-15% of total h beta 2 cDNA in the 10 brain substructures tested. Analysis of human genomic southern blots suggests that the two forms might arise by differential splicing.

    PMID: 7707873 [PubMed - indexed for MEDLINE]

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