Schizophr Bull. 1994;20(4):713-25.

Children with schizophrenia: diagnosis, phenomenology, and pharmacotherapy.

Source

Dept. of Psychiatry, New York University School of Medicine, NY 10016.

Abstract

This article presents data on the diagnosis and phenomenology of schizophrenia in 16 hospitalized children, ages 5.5 to 11.75 years. These 16 subjects are the first to complete an ongoing double-blind, placebo-controlled study of haloperidol in children with schizophrenia diagnosed by DSM-III-R criteria. We describe the pharmacologic treatment response of this subsample and compare our diagnostic, phenomenologic, and treatment findings with those of other investigators. Our results show that children under age 12 can be diagnosed with schizophrenia by the same criteria used for adults, that they show comparable clinical symptoms, and that on haloperidol they show improvement in target psychotic symptoms, at least in a short-term inpatient setting.

PMID:: 7701278; [PubMed - indexed for MEDLINE]

Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Molecular Biology Databases

HALOPERIDOL - HSDB

Supplemental Content

Save items

Related citations in PubMed

An open trial of clozapine in 11 adolescents with childhood-onset schizophrenia. [J Am Acad Child Adolesc Psychi...]
An open trial of clozapine in 11 adolescents with childhood-onset schizophrenia.
Frazier JA, Gordon CT, McKenna K, Lenane MC, Jih D, Rapoport JL. J Am Acad Child Adolesc Psychiatry. 1994 Jun; 33(5):658-63.
Haloperidol in schizophrenic children: early findings from a study in progress. [Psychopharmacol Bull. 1992]
Haloperidol in schizophrenic children: early findings from a study in progress.
Spencer EK, Kafantaris V, Padron-Gayol MV, Rosenberg CR, Campbell M. Psychopharmacol Bull. 1992; 28(2):183-6.
Childhood-onset schizophrenia. A double-blind clozapine-haloperidol comparison. [Arch Gen Psychiatry. 1996]
Childhood-onset schizophrenia. A double-blind clozapine-haloperidol comparison.
Kumra S, Frazier JA, Jacobsen LK, McKenna K, Gordon CT, Lenane MC, Hamburger SD, Smith AK, Albus KE, Alaghband-Rad J, et al. Arch Gen Psychiatry. 1996 Dec; 53(12):1090-7.
Review The clinical presentation of childhood-onset schizophrenia. [Schizophr Bull. 1994]
Review The clinical presentation of childhood-onset schizophrenia.
Russell AT. Schizophr Bull. 1994; 20(4):631-46.
Review Amisulpride compared with standard neuroleptics in acute exacerbations of schizophrenia: three efficacy studies. [Int Clin Psychopharmacol. 1997]
Review Amisulpride compared with standard neuroleptics in acute exacerbations of schizophrenia: three efficacy studies.
Freeman HL. Int Clin Psychopharmacol. 1997 May; 12 Suppl 2:S11-7.

See reviews... See all...

Cited by 4 PubMed Central articles

Semantic Processing and Thought Disorder in Childhood-Onset Schizophrenia: Insights from fMRI. [J Neurolinguistics. 2010]
Semantic Processing and Thought Disorder in Childhood-Onset Schizophrenia: Insights from fMRI.
Borofsky LA, McNealy K, Siddarth P, Wu KN, Dapretto M, Caplan R. J Neurolinguistics. 2010 May; 23(3):204-222.
Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients. [Neuropsychiatr Dis Treat. 2010]
Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients.
Maloney AE, Sikich L. Neuropsychiatr Dis Treat. 2010 Nov 10; 6:749-66. Epub 2010 Nov 10.
Study of childhood onset schizophrenia (COS) using SPECT and neuropsychological assessment. [Indian J Psychiatry. 2006]
Study of childhood onset schizophrenia (COS) using SPECT and neuropsychological assessment.
Malhotra S, Gupta N, Bhattacharya A, Kapoor M. Indian J Psychiatry. 2006 Oct; 48(4):215-22.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Children with schizophrenia: diagnosis, phenomenology, and pharmacotherapy.
Children with schizophrenia: diagnosis, phenomenology, and pharmacotherapy.
Schizophr Bull. 1994 ;20(4):713-25.

PubMed
The antipsoriatic Mahonia aquifolium and its active constituents; II. Antiprolif...
The antipsoriatic Mahonia aquifolium and its active constituents; II. Antiproliferative activity against cell growth of human keratinocytes.
Planta Med. 1995 Feb ;61(1):74-5.

PubMed
Time estimation deficits in developmental dyslexia: evidence of cerebellar invol...
Time estimation deficits in developmental dyslexia: evidence of cerebellar involvement.
Proc Biol Sci. 1995 Jan 23 ;259(1354):43-7.

PubMed
The pathogenesis and long-term end results of pigmented villonodular synovitis.
The pathogenesis and long-term end results of pigmented villonodular synovitis.
Clin Orthop Relat Res. 1976 Jan-Feb ;(114):335-51.

PubMed
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors.
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors.
Nature. 1995 Apr 6 ;374(6522):569-71.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Children with schizophrenia: diagnosis, phenomenology, and pharmacotherapy.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 4 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information