FEBS Lett. 1995 Mar 20;361(2-3):201-5.

Novel modification of ceramide: rat glioma ganglioside GM3 having 3-O-acetylated sphingenine.

Suetake K, Tsuchihashi K, Inaba K, Chiba M, Ibayashi Y, Hashi K, Gasa S.

Source

Department of Neurological Surgery, School of Medicine, Sapporo Medical University, Japan.

Abstract

A novel O-acetylated GM3 containing 3-O-acetyl 4-sphingenine was isolated with one having a non-acetylated base from transplanted rat glioma tissue. The presence and position of the acetyl group were estimated by one- and two-dimensional proton nuclear magnetic resonance, and fast atom bombardment-mass spectrometries. In addition, the O-acetyl GM3 showed higher immunological activity toward anti-melanoma antibody in the presence of non-acetylated GM3 in complement-dependent liposome lysis than did non-acetylated or acetylated GM3 alone in the liposome, suggesting enhancement of immunological reactivity of the intact tumor cells by a small amount of O-acetyl GM3.

PMID:: 7698323; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Antigenicity of the carbohydrate moiety of ganglioside GM3 having 3-O-acetyl ceramide. [Glycoconj J. 1999]
Antigenicity of the carbohydrate moiety of ganglioside GM3 having 3-O-acetyl ceramide.
Daino T, Tsuchihashi K, Kashiwagi M, Yachida Y, Akino T, Gasa S. Glycoconj J. 1999 Jan; 16(1):39-43.
Synthesis of a glioma-related ganglioside, O-Ac GM3 having 3-O-Ac ceramide and its substrate property toward hydrolases. [J Lipid Res. 1996]
Synthesis of a glioma-related ganglioside, O-Ac GM3 having 3-O-Ac ceramide and its substrate property toward hydrolases.
Tsuchihashi K, Daino T, Akino T, Gasa S. J Lipid Res. 1996 Oct; 37(10):2136-44.
Characterization of novel mono-O-acetylated GM3s containing 9-O-acetyl sialic acid and 6-O-acetyl galactose in equine erythrocytes. [Glycoconj J. 1996]
Characterization of novel mono-O-acetylated GM3s containing 9-O-acetyl sialic acid and 6-O-acetyl galactose in equine erythrocytes.
Yachida Y, Tsuchihashi K, Gasa S. Glycoconj J. 1996 Apr; 13(2):225-23.
Review Cancer vaccines: an update with special focus on ganglioside antigens. [Oncol Rep. 2002]
Review Cancer vaccines: an update with special focus on ganglioside antigens.
Bitton RJ, Guthmann MD, Gabri MR, Carnero AJ, Alonso DF, Fainboim L, Gomez DE. Oncol Rep. 2002 Mar-Apr; 9(2):267-76.
Review [Induction of anti-melanoma CTL by GM3 (NeuGc)-liposomes]. [Nihon Rinsho. 1990]
Review [Induction of anti-melanoma CTL by GM3 (NeuGc)-liposomes].
Harada Y, Taniguchi M. Nihon Rinsho. 1990 Feb; 48(2):411-6.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Novel modification of ceramide: rat glioma ganglioside GM3 having 3-O-acetylated...
Novel modification of ceramide: rat glioma ganglioside GM3 having 3-O-acetylated sphingenine.
FEBS Lett. 1995 Mar 20 ;361(2-3):201-5.

PubMed
Toward an understanding of the formylation of initiator tRNA methionine in proka...
Toward an understanding of the formylation of initiator tRNA methionine in prokaryotic protein synthesis. II. A two-state model for the 70S ribosome.
Biochemistry. 1976 Apr 6 ;15(7):1362-9.

PubMed
Antagonistic regulation of alpha 2-adrenoceptors by neuropeptide Y receptor subt...
Antagonistic regulation of alpha 2-adrenoceptors by neuropeptide Y receptor subtypes in the nucleus tractus solitarii.
Eur J Pharmacol. 1994 Dec 12 ;271(1):201-12.

PubMed
Evidence that pure uptake inhibitors including cocaine interact slowly with the ...
Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier.
Eur J Pharmacol. 1994 Nov 3 ;264(3):391-8.

PubMed
Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-bin...
Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family.
Cell. 1995 Mar 24 ;80(6):899-908.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Novel modification of ceramide: rat glioma ganglioside GM3 having 3-O-acetylated sphingenine.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information