Hepatobiliary cystadenoma with mesenchymal stroma: expression of oestrogen receptors in formalin-fixed tissue

F R Scott; L More; A P Dhillon

doi:10.1111/j.1365-2559.1995.tb00274.x

Hepatobiliary cystadenoma with mesenchymal stroma: expression of oestrogen receptors in formalin-fixed tissue

Histopathology. 1995 Jun;26(6):555-8. doi: 10.1111/j.1365-2559.1995.tb00274.x.

Authors

F R Scott¹, L More, A P Dhillon

Affiliation

¹ Department of Histopathology, Royal Free Hospital and School of Medicine, London, UK.

PMID: 7665146
DOI: 10.1111/j.1365-2559.1995.tb00274.x

Abstract

We report three cases of hepatobiliary cystadenoma with mesenchymal stroma in which oestrogen receptor immunostaining was carried out, after using a microwave method of antigen retrieval. In one of the tumours immunoreactivity for oestrogen receptors was demonstrated within the mesenchymal stromal cells. The presence of oestrogen receptors supports the theory that oestrogens act as tumour promoters and may explain the female predilection.

Publication types

Case Reports

MeSH terms

Adult
Biliary Tract Neoplasms / chemistry
Biliary Tract Neoplasms / pathology*
Cystadenoma / chemistry
Cystadenoma / pathology*
Female
Formaldehyde
Humans
Immunoenzyme Techniques
Liver Neoplasms / chemistry
Liver Neoplasms / pathology*
Mesoderm / chemistry
Middle Aged
Paraffin Embedding
Receptors, Estrogen / analysis*
Receptors, Estrogen / immunology
Stromal Cells / immunology
Stromal Cells / pathology
Tissue Fixation

Substances

Receptors, Estrogen
Formaldehyde