Nat Struct Biol. 1995 May;2(5):350-4.

LRRning the RIte of springs.

Abstract

The determination of the crystal structure of the ribonuclease inhibitor-ribonuclease A complex provides exciting new insight on how the leucine-rich repeat allows a single molecule to get around the problem of inhibiting an entire family of enzymes.

PMID:: 7664088; [PubMed - indexed for MEDLINE]

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Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. [Nature. 1993]
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats.
Kobe B, Deisenhofer J. Nature. 1993 Dec 23-30; 366(6457):751-6.
Modular mutagenesis of human placental ribonuclease inhibitor, a protein with leucine-rich repeats. [Proc Natl Acad Sci U S A. 1990]
Modular mutagenesis of human placental ribonuclease inhibitor, a protein with leucine-rich repeats.
Lee FS, Vallee BL. Proc Natl Acad Sci U S A. 1990 Mar; 87(5):1879-83.
A structural basis of the interactions between leucine-rich repeats and protein ligands. [Nature. 1995]
A structural basis of the interactions between leucine-rich repeats and protein ligands.
Kobe B, Deisenhofer J. Nature. 1995 Mar 9; 374(6518):183-6.
Review Proteins with leucine-rich repeats. [Curr Opin Struct Biol. 1995]
Review Proteins with leucine-rich repeats.
Kobe B, Deisenhofer J. Curr Opin Struct Biol. 1995 Jun; 5(3):409-16.
Review The leucine-rich repeat: a versatile binding motif. [Trends Biochem Sci. 1994]
Review The leucine-rich repeat: a versatile binding motif.
Kobe B, Deisenhofer J. Trends Biochem Sci. 1994 Oct; 19(10):415-21.

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Cited by 3 PubMed Central articles

Review Ribonuclease inhibitor: structure and function. [Prog Nucleic Acid Res Mol Biol...]
Review Ribonuclease inhibitor: structure and function.
Dickson KA, Haigis MC, Raines RT. Prog Nucleic Acid Res Mol Biol. 2005; 80:349-74.
Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution. [EMBO J. 1997]
Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution.
Papageorgiou AC, Shapiro R, Acharya KR. EMBO J. 1997 Sep 1; 16(17):5162-77.
Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A. [Proc Natl Acad Sci U S A. 1997]
Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A.
Chen CZ, Shapiro R. Proc Natl Acad Sci U S A. 1997 Mar 4; 94(5):1761-6.

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Nat Struct Biol. 1995 May ;2(5):350-4.

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