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J Urol. 1995 Oct;154(4):1302-6.

Nuclear morphometry in differential diagnosis of renal oncocytoma and renal cell carcinoma.

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  • 1Department of Pathology, University of Turku, Finland.

Abstract

PURPOSE:

Morphometric distinction of renal oncocytoma and renal cell carcinoma was attempted.

MATERIALS AND METHODS:

Nuclear morphometric measurements were done from sections of 16 histologically diagnosed renal oncocytomas and renal cell carcinoma controls (grade 1 or 2, stage T1 to 2N0M0).

RESULTS:

Oncocytomas could be distinguished from carcinomas on the basis of nuclear morphometry in more than 80% of the cases. Especially, the shape descriptors (form factors) were significantly different between oncocytomas and carcinomas.

CONCLUSIONS:

Morphometrically determined nuclear shape descriptors can be used to support diagnostic decisions in problematic cases.

PMID:
7658524
[PubMed - indexed for MEDLINE]
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