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Eur J Obstet Gynecol Reprod Biol. 1995 Apr;59(2):149-51.

Hyponatraemia and non-electrolyte solutions in labouring primigravida.

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  • 1National Maternity Hospital, Dublin, Ireland.


We performed a prospective randomised study on one hundred primigravid women who required oxytocin to augment labour, comparing dextrose infusion with normal saline. After delivery, the 45 patients whose oxytocin was infused in dextrose had significantly lower serum sodium levels in both mother and baby compared to the 48 patients who had their oxytocin administered in normal saline. This was particularly evident in those cases where epidural analgesia was employed.

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