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Trends Microbiol. 1995 Jun;3(6):229-36.

Unconstrained bacterial promiscuity: the Tn916-Tn1545 family of conjugative transposons.

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  • 1Dept of Biologic and Materials Sciences, School of Dentistry, School of Medicine, University of Michigan, Ann Arbor 48109, USA.


Conjugative transposons are highly ubiquitous elements found throughout the bacterial world. Members of the Tn916-Tn1545 family carry the widely disseminated tetracycline-resistance determinant Tet M, as well as additional resistance genes. They have been found naturally in, or been introduced into, over 50 different species and 24 genera of bacteria. Recent investigations have led to insights into the molecular basis of movement of these interesting mobile elements.

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