Abstract
Activation of pro-sigma K processing in the mother cell at late stages of sporulation in Bacillus subtilis requires the presence of active sigma G in the forespore. Placing the spoIVB gene under the control of sigma F, the early forespore transcription factor, allows sigma K to become active in the absence of sigma G. Therefore, transcription of spoIVB is the only role of sigma G that is essential for the signaling pathway between sigma G and sigma K.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacillus subtilis / genetics
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Bacillus subtilis / physiology*
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Bacterial Proteins / genetics*
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DNA-Directed RNA Polymerases / metabolism
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Gene Expression Regulation, Bacterial
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Membrane Proteins*
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Protein Precursors / metabolism
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Protein Processing, Post-Translational*
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Sigma Factor / metabolism*
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Spores, Bacterial / genetics
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Spores, Bacterial / growth & development
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Time Factors
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Transcription Factors / metabolism
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Transcription, Genetic*
Substances
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Bacterial Proteins
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Membrane Proteins
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Protein Precursors
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Sigma Factor
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Transcription Factors
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sigma K
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spoIV protein, Bacillus megaterium
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RNA polymerase sigma G
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DNA-Directed RNA Polymerases