Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nature. 1995 Aug 10;376(6540):490-8.

Structure of serum response factor core bound to DNA.

Author information

  • 1Institut für Molekularbiologie und Biophysik, ETH-Hönggerberg, Zürich, Switzerland.

Abstract

The human serum response factor is a transcription factor belonging to the MADS domain protein family with members characterized from the plant and animal kingdoms. The X-ray crystal structure of the serum response factor core in a specific-recognition DNA complex shows that the functions of DNA binding, dimerization and accessory-factor interaction are compactly integrated into a novel protein unit. The intrinsic and induced conformation of the serum response element DNA is the principal DNA feature recognized in the specific complex.

Comment in

PMID:
7637780
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk