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J Med Assoc Thai. 1995 Jan;78(1):11-7.

Production of monoclonal antibody against hepatitis B surface antigen.

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  • 1Institute of Pre-Clinical Sciences, Faculty of Medicine, Thammasat University, Pratumthani, Thailand.


HBV infection is a major health problem in Southeast Asia. Thailand is considered to be an endemic area of HBV infection(18). Prevalence of HBsAg carriers is 5.2 per cent in children, 9 per cent in adults and 5.6 per cent in pregnant women(19,20). We believe that the monoclonal antibody described in the present report will be useful to develop HBsAg-KIT for national serologic screening assay, as considered in terms of sensitivity, specificity and cost effectiveness.

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