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    Biochim Biophys Acta. 1995 Jul 13;1257(2):199-202.

    Cloning and chromosomal localization of the human ileal lipid-binding protein.

    Oelkers P, Dawson PA.

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    Department of Internal Medicine-Gastroenterology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157, USA.

    Abstract

    A human ileal lipid-binding protein (ILBP3) cDNA was isolated and shown to encode a 128 amino acid protein with homology to the fatty acid-binding protein gene family. The human ILBP amino acid sequence exhibited 78% identity to the rat ILBP sequence. Northern blot analysis revealed a single transcript of approx. 0.6 kb in small intestine, but no hybridization to liver, spleen, thymus, prostate, ovary, caecum, or colon. Southern blot analysis of genomic DNA from a panel of rodent-human somatic cell hybrids revealed that the human ILBP gene resides on chromosome 5 and is not linked to any other known fatty acid-binding protein family member.

    PMID:
    7619861
    [PubMed - indexed for MEDLINE]

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