Identification of additional homologues of subunits VII and VIII of the ubiquinol-cytochrome c oxidoreductase enables definition of consensus sequences

H Boumans; J A Berden; L A Grivell

doi:10.1016/0014-5793(95)00611-c

Identification of additional homologues of subunits VII and VIII of the ubiquinol-cytochrome c oxidoreductase enables definition of consensus sequences

FEBS Lett. 1995 Jul 10;368(1):105-9. doi: 10.1016/0014-5793(95)00611-c.

Authors

H Boumans¹, J A Berden, L A Grivell

Affiliation

¹ E.C. Slater Institute, University of Amsterdam, The Netherlands.

PMID: 7615060
DOI: 10.1016/0014-5793(95)00611-c

Abstract

The Candida utilis QCR7 gene encoding subunit VII of the ubiquinol-cytochrome c oxidoreductase was isolated by functional complementation of the Saccharomyces cerevisiae subunit VII-null mutant. Several other subunit VII homologues as well as homologues for subunit VIII were identified by screening the GenBank database. Some of these homologues for subunit VII could only be identified as such using a consensus sequence that was derived from the multiple sequence alignment. Definition of the consensus should facilitate further analysis of structure/function relationships in this protein.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Base Sequence
Candida / genetics
Consensus Sequence*
DNA, Fungal
Databases, Factual
Electron Transport Complex III / chemistry*
Electron Transport Complex III / genetics
Escherichia coli
Genes, Fungal
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae / genetics
Sequence Homology, Amino Acid

Substances

DNA, Fungal
Electron Transport Complex III

Associated data

GENBANK/U20215