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Trends Microbiol. 1995 Apr;3(4):136-40.

The role of cytokines in gram-positive bacterial shock.

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  • 1Eijkman-Winkler Institute of Medical and Clinical Microbiology, University Hospital Utrecht, The Netherlands.


In Gram-positive bacterial shock, little is known about the sequence of events that controls the signalling of monocytes and macrophages that leads to the release of cytokines. Cell-wall components, such as peptidoglycan and teichoic acid, are clearly important in the activation of these cells, but exotoxins may also be involved.

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