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Gene. 1995 May 19;157(1-2):213-5.

Growth-rate-dependent transcription initiation from the dam P2 promoter.

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  • 1Department of Pharmacology, University of Massachusetts Medical School, Worcester 01655, USA.


Transcription of the dam gene in Escherichia coli is dependent on growth rate. Using single-copy promoter::lacZYA fusions we found that of the five promoter regions which affect dam expression, only the P2 promoter shows growth-rate dependence. The determinants for growth-rate control must lie in the region -52 to +27 relative to the transcription start point.

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