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Clin Genet. 1995 Feb;47(2):80-4.

Congenital cardiac malformations in Adams-Oliver syndrome.

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  • 1Ray and Hattie Anderson Center for the Study of Hereditary Cardiac Disease, Department of Pediatrics, Variety Club Children's Hospital, University of Minnesota, Minneapolis 55455, USA.


Two patients with Adams-Oliver syndrome and congenital cardiac malformations are described. A literature review revealed at 13.4% occurrence of congenital cardiac malformations in individuals with Adams-Oliver syndrome, suggesting that cardiac anomalies are a frequent manifestation of this syndrome. All patients with Adams-Oliver syndrome (aplasia cutis congenita and terminal digital anomalies) should be evaluated for cardiac anomalies.

[PubMed - indexed for MEDLINE]
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