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Curr Biol. 1995 Aug 1;5(8):859-61.

Transcriptional regulation. Flipping the Myc switch.

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  • Division of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam.

Abstract

When certain cells differentiate, Myc in Myc-Max heterodimers is replaced by Mad or Mxi, generating heterodimers that suppress transcription by interacting with the repressor Sin3.

PMID:
7583141
[PubMed - indexed for MEDLINE]
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