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Immunol Today. 1995 Oct;16(10):495-500.

Linkage of cell-mediated immunity to iron metabolism.

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  • 1Dept of Internal Medicine, University of Innsbruck Hospital, Austria.


Iron is essential for growing microorganisms and tumour cells, and is also crucial for the proliferation of immune cells. In this review, G√ľnter Weiss, Helmut Wachter and Dietmar Fuchs focus on the complex network of interactions that link iron metabolism with cellular immune effector functions involving cytokines and nitric oxide, and draw a suitable model for the pathogenesis of anaemia of chronic disease.

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