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    Somat Cell Mol Genet. 1995 Mar;21(2):147-50.

    Identification of the human neuronal nicotinic cholinergic alpha 2 receptor locus, (CHRNA2), within an 8p21 mapped locus, by sequence homology with rat DNA.

    Wood S, Schertzer M, Yaremko ML.

    Department of Medical Genetics, University of British Columbia, Vancouver, Canada.

    We have identified a cosmid, at the D8S131 locus, that shows sequence homology with exon 2 of the rat gene for the neuronal nicotinic acetylcholine receptor alpha 2 subunit. A 357-bp sequence surrounding a rare cutter AscI site contains a 152-bp region of homology. The human CHRNA2 gene is therefore positioned at the D8S131 locus, which has been mapped to 8p21.

    PMID: 7570187 [PubMed - indexed for MEDLINE]

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