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J Urol. 1995 Nov;154(5):1770-4.

Benign prostatic hyperplasia specific health status measures in clinical research: how much change in the American Urological Association symptom index and the benign prostatic hyperplasia impact index is perceptible to patients?

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  • 1Medical Practices Evaluation Center, Massachusetts General Hospital, Boston, USA.

Abstract

PURPOSE:

We assessed the relationship between changes in scores for the American Urological Association (AUA) symptom index and benign prostatic hyperplasia (BPH) impact index with patient global ratings of improvement in a large Veterans Affairs trial comparing different pharmacological therapies for BPH.

MATERIALS AND METHODS:

The primary analyses compared absolute score changes from baseline with global ratings of improvement at 13 weeks for 1,218 men.

RESULTS:

Subjects who rated themselves as being slightly improved had a mean decrease in AUA symptom index and BPH impact index scores of 3.1 and 0.4 points, respectively. However, the baseline scores strongly influenced this relationship.

CONCLUSIONS:

These data provide guidance for investigators using the AUA symptom index and BPH impact index as outcome measures.

PMID:
7563343
[PubMed - indexed for MEDLINE]
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